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X-ray image of hands illustrating radiographic progression in rheumatoid arthritis, with focus on joints affected by arthritis.

High rheumatoid factor levels (above 200 IU/ml) are associated with higher probability of radiographic progression9

Learn about recent data and their impact on rheumatoid arthritis clinical management

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Personalizing approaches to rheumatoid arthritis treatment. What role could rheumatoid factor play?

  • 1937

    Rheumatoid factor first discovered in a patient with rheumatoid arthritis1

  • 1956

    Included in the ARA diagnostic criteria for definite rheumatoid arthritis as “positive sheep cell agglutination”2

  • 1958

    Characterization of antibodies and gamma globulin that interact with rheumatoid factor3